Paper card · curated
Cannabidiol in anxiety and sleep: a large case series
Shannon S, Lewis N, Lee H, Hughes S
The Permanente Journal · 2019
Abstract excerpt
Retrospective chart review of 72 adult psychiatric patients receiving CBD as adjunctive treatment in an outpatient setting. Anxiety scores decreased in the first month for 79.2% of patients and remained decreased at month 3. Sleep scores improved within the first month for 66.7% of patients but fluctuated over time. CBD was generally well-tolerated; only 3 patients discontinued due to side effects. Findings are consistent with prior preclinical evidence and warrant controlled investigation.
Excerpt from the published abstract. Full paper at the journal link below.
Joe's notes
How to read this paper
Frequently cited in CBD wellness marketing — read the methodology. It's a chart review (not a controlled trial), open-label, with all the caveats that apply to that design. Real signal worth taking seriously, real limits worth respecting.
Read the paper
FDA disclaimer
Research papers in this library describe published scientific findings. They are not therapeutic claims. These statements have not been evaluated by the FDA. Compounds discussed in any paper are not intended to diagnose, treat, cure, or prevent any disease. Talk to a healthcare provider before making decisions about supplements.