Paper card · curated
Erinacines A, B, and C, strong stimulators of nerve growth factor synthesis from the mycelia of Hericium erinaceum
Kawagishi H, Shimada A, Shirai R, Okamoto K, Ojima F, et al.
Tetrahedron Letters · 1994
Abstract excerpt
Three novel diterpenoids, erinacines A, B, and C, were isolated from the mycelia of Hericium erinaceum. All three induce nerve growth factor (NGF) synthesis with substantially higher potency than hericenones. The compounds appear concentrated in the mycelial fraction rather than the fruit body, which has implications for product formulation and supplement-industry labeling.
Excerpt from the published abstract. Full paper at the journal link below.
Joe's notes
How to read this paper
Companion paper to the 1991 hericenones isolation. Critical for understanding the fruit-body-vs-mycelium distinction in supplement labeling: hericenones are in fruit body, erinacines are in mycelium. Both are NGF-inducing diterpenoids; products should disclose which fraction they're using.
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